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Does elevated intraocular pressure reduce retinal TRKB-mediated survival signaling in experimental glaucoma?

Reduced retrograde transport of neurotrophins (NT) and their receptors has been hypothesized to contribute directly to retinal ganglion cell (RGC) loss in glaucoma. However, strategies of supplementing NT and NT receptors have failed to avert ultimate RGC death in experimental glaucoma. This study e...

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Detalhes bibliográficos
Main Authors: Guo, Ying, Johnson, Elaine, Cepurna, William, Jia, Lijun, Dyck, Jennifer, Morrison, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783343/
https://ncbi.nlm.nih.gov/pubmed/19682984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2009.08.003
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