Myelination in the absence of UDP-galactose:ceramide galactosyl-transferase and fatty acid 2 -hydroxylase

BACKGROUND: The sphingolipids galactosylceramide (GalCer) and sulfatide are major myelin components and are thought to play important roles in myelin function. The importance of GalCer and sulfatide has been validated using UDP-galactose:ceramide galactosyltransferase-deficient (Cgt(-/-)) mice, whic...

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Bibliographic Details
Main Authors: Meixner, Marion, Jungnickel, Julia, Grothe, Claudia, Gieselmann, Volkmar, Eckhardt, Matthias
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053264/
https://ncbi.nlm.nih.gov/pubmed/21366909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-22
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