Recombinant chimeric lectins consisting of mannose-binding lectin and L-ficolin are potent inhibitors of influenza A virus compared with mannose-binding lectin

MBL structurally contains a type II-like collagenous domain and a carbohydrate recognition domain (CRD). We have recently generated three novel recombinant chimeric lectins (RCL), in which varying length of collagenous domain of mannose-binding lectin (MBL) is replaced with that of L-ficolin (L-FCN)...

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Main Authors: Chang, Wei-Chuan, Hartshorn, Kevan L., White, Mitchell R., Moyoa, Patience, Michelow, Ian C., Koziel, Henry, Kinane, Bernard T., Schmidt, Emmett V., Fujita, Teizo, Takahashi, Kazue
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053085/
https://ncbi.nlm.nih.gov/pubmed/21035429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.10.012
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