A Novel L-ficolin/Mannose-binding Lectin Chimeric Molecule with Enhanced Activity against Ebola Virus

Ebola viruses constitute a newly emerging public threat because they cause rapidly fatal hemorrhagic fevers for which no treatment exists, and they can be manipulated as bioweapons. We targeted conserved N-glycosylated carbohydrate ligands on viral envelope surfaces using novel immune therapies. Man...

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Библиографические подробности
Главные авторы: Michelow, Ian C., Dong, Mingdong, Mungall, Bruce A., Yantosca, L. Michael, Lear, Calli, Ji, Xin, Karpel, Marshall, Rootes, Christina L., Brudner, Matthew, Houen, Gunnar, Eisen, Damon P., Kinane, T. Bernard, Takahashi, Kazue, Stahl, Gregory L., Olinger, Gene G., Spear, Gregory T., Ezekowitz, R. Alan B., Schmidt, Emmett V.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Protein Structure and Folding
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915709/
https://ncbi.nlm.nih.gov/pubmed/20516066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106260
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