A Novel L-ficolin/Mannose-binding Lectin Chimeric Molecule with Enhanced Activity against Ebola Virus

Ebola viruses constitute a newly emerging public threat because they cause rapidly fatal hemorrhagic fevers for which no treatment exists, and they can be manipulated as bioweapons. We targeted conserved N-glycosylated carbohydrate ligands on viral envelope surfaces using novel immune therapies. Man...

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Main Authors: Michelow, Ian C., Dong, Mingdong, Mungall, Bruce A., Yantosca, L. Michael, Lear, Calli, Ji, Xin, Karpel, Marshall, Rootes, Christina L., Brudner, Matthew, Houen, Gunnar, Eisen, Damon P., Kinane, T. Bernard, Takahashi, Kazue, Stahl, Gregory L., Olinger, Gene G., Spear, Gregory T., Ezekowitz, R. Alan B., Schmidt, Emmett V.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915709/
https://ncbi.nlm.nih.gov/pubmed/20516066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106260
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