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Selenomethionine Inhibits IL-1β Inducible Nitric Oxide Synthase (iNOS) and Cyclooxygenase 2 (COX2) Expression in Primary Human Chondrocytes

OBJECTIVE: Several lines of evidence show that selenium has potential protective effects in osteoarthritis (OA), however the exact mechanism is still unclear. As IL-1β is one of the key proinflammatory cytokines contributing to the progression in OA, we investigated the effect of selenium in neutral...

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Detalhes bibliográficos
Main Authors: Cheng, Anthony Wai Ming, Stabler, Thomas V., Bolognesi, Michael, Kraus, Virginia Byers
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053078/
https://ncbi.nlm.nih.gov/pubmed/21035557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2010.10.019
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