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Limited Sufficiency of Antigen Presentation by Dendritic Cells in Models of Central Nervous System Autoimmunity

Experimental autoimmune encephalomyelitis (EAE), a model for the human disease multiple sclerosis (MS), is dependent upon the activation and effector functions of autoreactive CD4 T cells. Multiple interactions between CD4 T cells and major histocompatibility class II (MHCII)+ antigen presenting cel...

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Autores principales: Wu, Gregory F., Shindler, Kenneth S., Allenspach, Eric J., Stephen, Tom L., Thomas, Hannah L., Mikesell, Robert J., Cross, Anne H., Laufer, Terri M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053076/
https://ncbi.nlm.nih.gov/pubmed/21095100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2010.10.006
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