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MYELIN ANTIGEN LOAD INFLUENCES ANTIGEN PRESENTATION AND SEVERITY OF CENTRAL NERVOUS SYSTEM AUTOIMMUNITY
This study was designed to understand the impact of self-antigen load on manifestation of organ specific autoimmunity. Using a transgenic mouse model characterized by CNS hypermyelination, we show that larger myelin content results in greater severity of experimental autoimmune encephalomyelitis att...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653999/ https://ncbi.nlm.nih.gov/pubmed/23601904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2013.03.012 |
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