Identification of the primary mechanism of complement evasion by the periodontal pathogen, Treponema denticola

Treponema denticola, a periodontal pathogen, binds the complement regulatory protein, Factor H (FH). FhbB (FH binding protein B) is the sole FH binding protein produced by T.denticola. The interaction of FhbB with FH is unique in that FH is bound to the cell and then cleaved by the T.denticola prote...

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Bibliographic Details
Main Authors: McDowell, John V., Frederick, Jesse, Miller, Daniel P., Goetting-Minesky, M. Paula, Goodman, Heather, Fenno, J. Christopher, Marconi, Richard T.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053026/
https://ncbi.nlm.nih.gov/pubmed/21375704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2041-1014.2010.00598.x
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