PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia

OBJECTIVES: To explore mechanisms through which altered peroxisome proliferator–activated receptor γ coactivator 1α (PGC-1α) expression may influence Alzheimer disease (AD) amyloid neuropathology and to test the hypothesis that promotion of PGC-1α expression in neurons might be developed as a novel...

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Bibliografiske detaljer
Main Authors: Qin, Weiping, Haroutunian, Vahram, Katsel, Pavel, Cardozo, Christopher P., Ho, Lap, Buxbaum, Joseph D., Pasinetti, Giulio M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052997/
https://ncbi.nlm.nih.gov/pubmed/19273754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2008.588
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