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Chronic Granulomatous Disease: Lessons from a Rare Disorder
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency with x-linked or autosomal recessive inheritance involving defects in genes encoding phox proteins which are the subunits of the phagocyte NADPH oxidase. This results in failure to produce superoxide anion and downstream antimicr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3052948/ https://ncbi.nlm.nih.gov/pubmed/21195301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2010.09.008 |
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