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FGF2 Sustains NANOG and Switches the Outcome of BMP4 Induced Human Embryonic Stem Cell Differentiation
Here we show that as human embryonic stem (ES) cells exit the pluripotent state, NANOG can play a key role in determining lineage outcome. It has previously been reported that BMPs induce differentiation of human ES cells into extraembryonic lineages. Here we find that FGF2, acting through the MEK-E...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3052735/ https://ncbi.nlm.nih.gov/pubmed/21362572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.01.001 |
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