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The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer

We have generated a mouse model for pancreatic cancer through the somatic delivery of oncogene-bearing avian retroviruses to mice that express TVA, the receptor for avian leukosis sarcoma virus subgroup A (ALSV-A), under the control of the elastase promoter. Delivery of ALSV-A-based RCAS vectors enc...

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Autori principali: Lewis, Brian C., Klimstra, David S., Varmus, Harold E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC305263/
https://ncbi.nlm.nih.gov/pubmed/14681205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1140403
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