Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

How dividing mammalian cells overcome blocks to DNA replication by DNA damage, depleted nucleotide pools, or template-bound proteins is unclear. Here, we show that the response to blocked replication requires BRCA2, a suppressor of human breast cancer. By using two-dimensional gel electrophoresis, w...

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Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Lomonosov, Mikhail, Anand, Shubha, Sangrithi, Mahesh, Davies, Rachel, Venkitaraman, Ashok R.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Research Communications
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305253/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14681210/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.279003
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