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Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein
How dividing mammalian cells overcome blocks to DNA replication by DNA damage, depleted nucleotide pools, or template-bound proteins is unclear. Here, we show that the response to blocked replication requires BRCA2, a suppressor of human breast cancer. By using two-dimensional gel electrophoresis, w...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305253/ https://ncbi.nlm.nih.gov/pubmed/14681210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.279003 |
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