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Modification of DNA ends can decrease end joining relative to homologous recombination in mammalian cells.

In animal cells, exogenous DNA recombines into random chromosomal sites much more frequently than it recombines into homologous sites. Free DNA ends are "recombinogenic" in both processes. To test the effects of specific ends on analogous extrachromosomal processes, we constructed a linear...

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Bibliografske podrobnosti
Main Authors: Chang, X B, Wilson, J H
Format: Artigo
Jezik:Inglês
Izdano: 1987
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC305226/
https://ncbi.nlm.nih.gov/pubmed/3037530
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