Metal-dependent folding of a single zinc finger from transcription factor IIIA.

A 30-amino acid peptide, which corresponds to the second "zinc finger" domain of transcription factor IIIA, has been synthesized and purified. This peptide folds in the presence of zinc: adding Zn2+ significantly changes the circular dichroism spectrum, and Zn2+ protects the peptide from tryptic dig...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Frankel, A D, Berg, J M, Pabo, C O
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1987
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3474629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.14.4841
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