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Metal-dependent folding of a single zinc finger from transcription factor IIIA.

A 30-amino acid peptide, which corresponds to the second "zinc finger" domain of transcription factor IIIA, has been synthesized and purified. This peptide folds in the presence of zinc: adding Zn2+ significantly changes the circular dichroism spectrum, and Zn2+ protects the peptide from t...

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Autors principals: Frankel, A D, Berg, J M, Pabo, C O
Format: Artigo
Idioma:Inglês
Publicat: 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC305201/
https://ncbi.nlm.nih.gov/pubmed/3474629
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