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Splice-variant changes of the Ca(V)3.2 T-type calcium channel mediate voltage-dependent facilitation and associate with cardiac hypertrophy and development

Low voltage-activated T-type calcium (Ca) channels contribute to the normal development of the heart and are also implicated in pathophysiological states such as cardiac hypertrophy. Functionally distinct T-type Ca channel isoforms can be generated by alternative splicing from each of three differen...

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Detalhes bibliográficos
Main Authors: David, Laurence S, Garcia, Esperanza, Cain, Stuart M, Thau, Elana M, Tyson, John R, Snutch, Terrance P
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051872/
https://ncbi.nlm.nih.gov/pubmed/20699644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.4.5.12874
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