Determination of the minimum polypeptide lengths of the functionally active sites of human interleukins 1 alpha and 1 beta.
Interleukin 1 (IL-1) is a two-member family of proteins (IL-1 alpha and IL-1 beta) that mediates a diverse series of immune and inflammatory responses. These two proteins have only 26% amino acid homology yet bind to the same receptor. It is of importance to define the active sites of these molecule...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1987
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305132/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2955410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.13.4572 |
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