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Determination of the minimum polypeptide lengths of the functionally active sites of human interleukins 1 alpha and 1 beta.

Interleukin 1 (IL-1) is a two-member family of proteins (IL-1 alpha and IL-1 beta) that mediates a diverse series of immune and inflammatory responses. These two proteins have only 26% amino acid homology yet bind to the same receptor. It is of importance to define the active sites of these molecule...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Mosley, B, Dower, S K, Gillis, S, Cosman, D
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1987
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305132/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2955410/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.13.4572
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