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Maximum-likelihood methods in cryo-EM. Part I: theoretical basis and overview of existing approaches

The maximum likelihood method provides a powerful approach for many problems in cryo-EM image processing. This contribution aims to provide an accessible introduction to the underlying theory and reviews existing applications in the field. In addition, current developments to reduce computational co...

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Detalhes bibliográficos
Main Authors: Sigworth, Fred J., Doerschuk, Peter C., Carazo, Jose-Maria, Scheres, Sjors H.W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051286/
https://ncbi.nlm.nih.gov/pubmed/20888965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(10)82011-7
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