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Ghrelin-induced activation of cAMP signal transduction and its negative regulation by endocannabinoids in the hippocampus

Increasing evidence indicates that the gut peptide ghrelin facilitates learning behavior and memory tasks. The present study demonstrates a cellular signaling mechanism of ghrelin in the hippocampus. Ghrelin stimulated CREB (cAMP response-element binding protein) through the activation of cAMP, prot...

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Autors principals: Cuellar, Jacquelynn N., Isokawa, Masako
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051029/
https://ncbi.nlm.nih.gov/pubmed/21187104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.12.024
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