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A Kinetic Aggregation Assay Enabling Selective and Sensitive Aβ Amyloid Quantification in Cells and Tissues

The process of amyloid-β (Aβ) fibril formation is genetically and pathologically linked to Alzheimer's disease (AD). Thus, a selective and sensitive method for the quantification of Aβ amyloid fibrils in complex biological samples enables a variety of hypotheses to be tested. Herein we report t...

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Détails bibliographiques
Auteurs principaux: Du, Deguo, Murray, Amber N., Cohen, Ehud, Kim, Hyun-Eui, Simkovsky, Ryan, Dillin, Andrew, Kelly, Jeffery W.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051019/
https://ncbi.nlm.nih.gov/pubmed/21268584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1013744
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