A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

Phagocytosis can be induced via the engagement of Fcγ receptors by antibody-opsonized material. Furthermore, the efficiency of antibody-induced effector functions has been shown to be dramatically modulated by changes in antibody glycosylation. Because infection can modulate antibody glycans, which...

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Autori principali: Ackerman, Margaret E., Moldt, Brian, Wyatt, Richard T, Dugast, Anne-Sophie, McAndrew, Elizabeth, Tsoukas, Stephen, Jost, Stephanie, Berger, Christoph T., Sciaranghella, Gaia, Liu, Qingquan, Irvine, Darrell J, Burton, Dennis R., Alter, Galit
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050993/
https://ncbi.nlm.nih.gov/pubmed/21192942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2010.12.016
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