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Acellular Pertussis Booster in Adolescents Induces Th1 and Memory CD8(+) T Cell Immune Response

In a number of countries, whole cell pertussis vaccines (wcP) were replaced by acellular vaccines (aP) due to an improved reactogenicity profile. Pertussis immunization leads to specific antibody production with the help of CD4(+) T cells. In earlier studies in infants and young children, wcP vaccin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rieber, Nikolaus, Graf, Anna, Hartl, Dominik, Urschel, Simon, Belohradsky, Bernd H., Liese, Johannes
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050840/
https://ncbi.nlm.nih.gov/pubmed/21408149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017271
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