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Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters

In the mid-1990s, whole-cell pertussis (wP) vaccines were associated with local and systemic adverse events that prompted their replacement with acellular pertussis (aP) vaccines in many high-income countries. In the past decade, rates of pertussis disease have increased in children receiving only a...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: da Silva Antunes, Ricardo, Babor, Mariana, Carpenter, Chelsea, Khalil, Natalie, Cortese, Mario, Mentzer, Alexander J., Seumois, Grégory, Petro, Christopher D., Purcell, Lisa A., Vijayanand, Pandurangan, Crotty, Shane, Pulendran, Bali, Peters, Bjoern, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118631/
https://ncbi.nlm.nih.gov/pubmed/29920186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121309
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