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The role of conformational entropy in molecular recognition by calmodulin

The physical basis for high affinity interactions involving proteins is complex and potentially involves a range of energetic contributions. Among these are changes in protein conformational entropy, which cannot yet be reliably computed from molecular structures. We have recently employed changes i...

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Bibliografiske detaljer
Main Authors: Marlow, Michael S., Dogan, Jakob, Frederick, Kendra K., Valentine, Kathleen G., Wand, A. Joshua
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050676/
https://ncbi.nlm.nih.gov/pubmed/20383153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.347
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