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Disulfide bond stabilization of the hexameric capsomer of human immunodeficiency virus

The HIV-1 capsid is modeled as a Fullerene cone that is composed of ~250 hexamers of the viral CA protein and 12 CA pentamers. Structures of CA hexamers have been difficult to obtain because the hexamer-stabilizing interactions are inherently weak, and CA tends to spontaneously assemble into capsid-...

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Bibliografische gegevens
Hoofdauteurs: Pornillos, Owen, Ganser-Pornillos, Barbie K., Banumathi, Sankaran, Hua, Yuanzi, Yeager, Mark
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050670/
https://ncbi.nlm.nih.gov/pubmed/20600115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.06.042
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