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Rearrangement and expression of rabbit immunoglobulin kappa light chain gene in transgenic mice.
To determine whether a foreign unrearranged immunoglobulin gene can be functionally rearranged and expressed in vivo, a rabbit b9 kappa light chain gene construct containing a single germ-line kappa chain variable (V) region gene (V kappa), the five kappa chain joining (J) segments (J kappa), and th...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1987
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305058/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3108888/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.12.4229 |
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