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Rearrangement and expression of rabbit immunoglobulin kappa light chain gene in transgenic mice.

To determine whether a foreign unrearranged immunoglobulin gene can be functionally rearranged and expressed in vivo, a rabbit b9 kappa light chain gene construct containing a single germ-line kappa chain variable (V) region gene (V kappa), the five kappa chain joining (J) segments (J kappa), and th...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Goodhardt, M, Cavelier, P, Akimenko, M A, Lutfalla, G, Babinet, C, Rougeon, F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305058/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3108888/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.12.4229
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