Heterotaxin: a novel TGF-β signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos

Disruptions of anatomical left-right asymmetry result in life-threatening heterotaxic birth defects in vital organs. We performed a small molecule screen for left-right asymmetry phenotypes in Xenopus embryos and discovered a novel pyridine analog, heterotaxin, which disrupts both cardiovascular and...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Dush, Michael K., McIver, Andrew L., Parr, Meredith A., Young, Douglas D., Fisher, Julie, Newman, Donna R., Sannes, Philip L., Hauck, Marlene L., Deiters, Alexander, Nascone-Yoder, Nanette
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050558/
https://ncbi.nlm.nih.gov/pubmed/21338922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.12.008
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky