Interferon-α and interleukin-12 are induced, respectively, by double-stranded DNA and single-stranded RNA in human myeloid dendritic cells

Dendritic cells (DCs) are initiators of innate immunity and acquired immunity as cells linking these two bio-defence systems through the production of cytokines such as interferon-α (IFN-α) and interleukin-12 (IL-12). Nucleic acids such as DNA from damaged cells or pathogens are important activators...

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Main Authors: Katashiba, Yuichi, Miyamoto, Rie, Hyo, Akira, Shimamoto, Keiko, Murakami, Naoko, Ogata, Makoto, Amakawa, Ryuichi, Inaba, Muneo, Nomura, Shosaku, Fukuhara, Shirou, Ito, Tomoki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050440/
https://ncbi.nlm.nih.gov/pubmed/20875078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03350.x
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