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Increased radiation-induced transformation in C3H/10T1/2 cells after transfer of an exogenous c-myc gene.

C3H/10T1/2 cells were infected with a retroviral vector expressing a mouse c-myc oncogene and a drug-selection marker. The resulting cells, morphologically indistinguishable from C3H/10T1/2, displayed a greatly enhanced sensitivity to neoplastic transformation by ionizing radiation or by a chemical...

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Detalhes bibliográficos
Main Authors: Sorrentino, V, Drozdoff, V, Zeitz, L, Fleissner, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305037/
https://ncbi.nlm.nih.gov/pubmed/3473497
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