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Acute ablation of Langerhans cells enhances skin immune responses
Understanding the function of Langerhans cells (LC) in vivo has been complicated by conflicting results from LC-deficient mice. HuLangerin-DTA mice constitutively lack LC and develop exaggerated contact-hypersensitivity (CHS) responses. MuLangerin-DTR mice allow for the inducible elimination of LC a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3050031/ https://ncbi.nlm.nih.gov/pubmed/20855870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001802 |
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