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Improved insulin sensitivity by calorie restriction is associated with reduction of ERK and p70(S6K) activities in the liver of obese Zucker rats

Calorie restriction (CR) improves obesity-related insulin resistance through undefined molecular mechanisms. Insulin receptor substrate (IRS)-1 serine/threonine kinases have been proposed to modulate insulin sensitivity through phosphorylation of IRS proteins. The aim of this study is to test the hy...

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Detalhes bibliográficos
Principais autores: Zheng, Yanbin, Zhang, Wenshuo, Pendleton, Elisha, Leng, Sanhua, Wu, Jiong, Chen, Ridong, Sun, Xiao Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050029/
https://ncbi.nlm.nih.gov/pubmed/19801385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-09-0181
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