Myocardial Fibrosis as an Early Manifestation of Hypertrophic Cardiomyopathy

BACKGROUND: Myocardial fibrosis is a hallmark of hypertrophic cardiomyopathy and a proposed substrate for arrhythmias and heart failure. In animal models, profibrotic genetic pathways are activated early, before hypertrophic remodeling. Data showing early profibrotic responses to sarcomere-gene muta...

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Autori principali: Ho, Carolyn Y., López, Begoña, Coelho-Filho, Otavio R., Lakdawala, Neal K., Cirino, Allison L., Jarolim, Petr, Kwong, Raymond, González, Arantxa, Colan, Steven D., Seidman, J.G., Díez, Javier, Seidman, Christine E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049917/
https://ncbi.nlm.nih.gov/pubmed/20818890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1002659
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