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T1 Measurements Identify Extracellular Volume Expansion in Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers With and Without Left Ventricular Hypertrophy

BACKGROUND: Myocardial fibrosis is a hallmark of hypertrophic cardiomyopathy (HCM) and a potential substrate for arrhythmias and heart failure. Sarcomere mutations appear to induce profibrotic changes before left ventricular hypertrophy (LVH) develops. To further evaluate these processes, we used ca...

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Autori principali: Ho, Carolyn Y., Abbasi, Siddique A., Neilan, Tomas G., Shah, Ravi V., Chen, Yucheng, Heydari, Bobak, Cirino, Allison L., Lakdawala, Neal K., Orav, E. John, González, Arantxa, López, Begoña, Díez, Javier, Jerosch-Herold, Michael, Kwong, Raymond Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769196/
https://ncbi.nlm.nih.gov/pubmed/23549607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCIMAGING.112.000333
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