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Monoclonal anti-idiotypic antibody mimics the CD4 receptor and binds human immunodeficiency virus.

A monoclonal anti-idiotypic (anti-Id) antibody, HF1.7, was generated against anti-Leu-3a, a mouse monoclonal antibody (mAb) specific for the CD4 molecule on human helper/inducer T lymphocytes. The anti-Id nature of HF1.7 was demonstrated by the following properties. (i) It reacted in a solid-phase i...

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Bibliographic Details
Main Authors: Chanh, T C, Dreesman, G R, Kennedy, R C
Format: Artigo
Language:Inglês
Published: 1987
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC304982/
https://ncbi.nlm.nih.gov/pubmed/3495801
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