Monoclonal anti-idiotypic antibody mimics the CD4 receptor and binds human immunodeficiency virus.
A monoclonal anti-idiotypic (anti-Id) antibody, HF1.7, was generated against anti-Leu-3a, a mouse monoclonal antibody (mAb) specific for the CD4 molecule on human helper/inducer T lymphocytes. The anti-Id nature of HF1.7 was demonstrated by the following properties. (i) It reacted in a solid-phase i...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1987
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304982/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3495801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.11.3891 |
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