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Selective resistance of bone marrow-derived hemopoietic progenitor cells to gliotoxin.

The fungal metabolite gliotoxin at low concentrations prevents mitogen stimulation of mature lymphocytes as a result of gliotoxin-induced genomic DNA degradation. Bone marrow, on the other hand, contains a subpopulation of cells resistant to gliotoxin at similar concentrations. This population inclu...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Müllbacher, A, Hume, D, Braithwaite, A W, Waring, P, Eichner, R D
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304968/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2438687/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.11.3822
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