Selective resistance of bone marrow-derived hemopoietic progenitor cells to gliotoxin.
The fungal metabolite gliotoxin at low concentrations prevents mitogen stimulation of mature lymphocytes as a result of gliotoxin-induced genomic DNA degradation. Bone marrow, on the other hand, contains a subpopulation of cells resistant to gliotoxin at similar concentrations. This population inclu...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1987
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304968/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2438687/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.11.3822 |
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