Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke

Reduced infarct volume in TLR2-knockout mice compared with C57Bl/6 wild-type mice has recently been shown in experimental stroke and confirmed in this study. We now also show a significant decrease of CD11b-positive cell counts and decreased neuronal death in the ischemic hemispheres of TLR2-deficie...

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Bibliografske podrobnosti
Main Authors: Ziegler, Gina, Freyer, Dorette, Harhausen, Denise, Khojasteh, Uldus, Nietfeld, Wilfried, Trendelenburg, George
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049529/
https://ncbi.nlm.nih.gov/pubmed/20842165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.161
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