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Assessment of the Therapeutic Potential of Metallothionein-II Application in Focal Cerebral Ischemia In Vitro and In Vivo

Metallothionein-II (MT-II) is an ubiquitously expressed small-molecular-weight protein and highly induced in various species and tissues upon stress, inflammation, and ischemia. MT-deficiency exacerbates ischemic injury in rodent stroke models in vitro and in vivo. However, there is conflicting data...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Eidizadeh, Abass, Khajehalichalehshtari, Manuel, Freyer, Dorette, Trendelenburg, George
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682799/
https://ncbi.nlm.nih.gov/pubmed/26658636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144035
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