Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI

Necrostatin-1 inhibits receptor-interacting protein (RIP)-1 kinase and programmed necrosis and is neuroprotective in adult rodent models. Owing to the prominence of necrosis and continuum cell death in neonatal hypoxia–ischemia (HI), we tested whether necrostatin was neuroprotective in the developin...

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Bibliografiske detaljer
Main Authors: Northington, Frances J, Chavez-Valdez, Raul, Graham, Ernest M, Razdan, Sheila, Gauda, Estelle B, Martin, Lee J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049482/
https://ncbi.nlm.nih.gov/pubmed/20571523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.72
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