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Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI

Necrostatin-1 inhibits receptor-interacting protein (RIP)-1 kinase and programmed necrosis and is neuroprotective in adult rodent models. Owing to the prominence of necrosis and continuum cell death in neonatal hypoxia–ischemia (HI), we tested whether necrostatin was neuroprotective in the developin...

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Detalhes bibliográficos
Main Authors: Northington, Frances J, Chavez-Valdez, Raul, Graham, Ernest M, Razdan, Sheila, Gauda, Estelle B, Martin, Lee J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049482/
https://ncbi.nlm.nih.gov/pubmed/20571523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.72
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