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How one bad protein spoils the barrel: structural details of β(2)- microglobulin amyloidogenicity
In this issue, Eichner et al. (2011) describe at atomic resolution the structure of an amyloidogenic state of β(2)-microglobulin and how it may corrupt a soluble counterpart in the pathological scenario that ensues when good proteins go to the ‘dark side’ and form infectious toxic amyloid.
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049456/ https://ncbi.nlm.nih.gov/pubmed/21255721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.01.003 |
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