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Developmental Shift of Cyclophilin D Contribution to Hypoxic-Ischemic Brain Injury

Cyclophilin D (CypD), a regulator of the mitochondrial membrane permeability transition pore (PTP), enhances Ca(2+)-induced mitochondrial permeabilization and cell death in the brain. However, the role of CypD in hypoxic-ischemic (HI) brain injury at different developmental ages is unknown. At postn...

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Détails bibliographiques
Auteurs principaux: Wang, Xiaoyang, Carlsson, Ylva, Basso, Emy, Zhu, Changlian, Rousset, Catherine I., Rasola, Andrea, Johansson, Bengt R., Blomgren, Klas, Mallard, Carina, Bernardi, Paolo, Forte, Michael A., Hagberg, Henrik
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049447/
https://ncbi.nlm.nih.gov/pubmed/19244535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5832-08.2009
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