An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis

Despite having distinct expression patterns and phenotypes in mutant mice, the myogenic regulatory factors Myf5 and MyoD have been considered to be functionally equivalent. Here, we report that these factors have a different response to DNA damage, due to the presence in MyoD and absence in Myf5 of...

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Dettagli Bibliografici
Autori principali: Innocenzi, Anna, Latella, Lucia, Messina, Graziella, Simonatto, Marta, Marullo, Fabrizia, Berghella, Libera, Poizat, Coralie, Shu, Chih-Wen, Wang, Jean Y J, Puri, Pier Lorenzo, Cossu, Giulio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
Soggetti:
Scientific Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049428/
https://ncbi.nlm.nih.gov/pubmed/21212806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.195
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