An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis

Despite having distinct expression patterns and phenotypes in mutant mice, the myogenic regulatory factors Myf5 and MyoD have been considered to be functionally equivalent. Here, we report that these factors have a different response to DNA damage, due to the presence in MyoD and absence in Myf5 of...

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Bibliographische Detailangaben
Hauptverfasser: Innocenzi, Anna, Latella, Lucia, Messina, Graziella, Simonatto, Marta, Marullo, Fabrizia, Berghella, Libera, Poizat, Coralie, Shu, Chih-Wen, Wang, Jean Y J, Puri, Pier Lorenzo, Cossu, Giulio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Scientific Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049428/
https://ncbi.nlm.nih.gov/pubmed/21212806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.195
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