An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis

Despite having distinct expression patterns and phenotypes in mutant mice, the myogenic regulatory factors Myf5 and MyoD have been considered to be functionally equivalent. Here, we report that these factors have a different response to DNA damage, due to the presence in MyoD and absence in Myf5 of...

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Main Authors: Innocenzi, Anna, Latella, Lucia, Messina, Graziella, Simonatto, Marta, Marullo, Fabrizia, Berghella, Libera, Poizat, Coralie, Shu, Chih-Wen, Wang, Jean Y J, Puri, Pier Lorenzo, Cossu, Giulio
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049428/
https://ncbi.nlm.nih.gov/pubmed/21212806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.195
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