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Active lytic infection of human primary tonsillar B cells by KSHV and its noncytolytic control by activated CD4(+) T cells

Kaposi sarcoma–associated herpesvirus (KSHV) is a B-lymphotropic virus whose primary site of replication is the oropharynx. KSHV can infect both T and B cells from primary tonsillar explant cultures. However, T cells do not support lytic replication, while B cells spontaneously produce substantial a...

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Detalhes bibliográficos
Main Authors: Myoung, Jinjong, Ganem, Don
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049404/
https://ncbi.nlm.nih.gov/pubmed/21339648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43755
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